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Immunogen sequence: APGGGQHGLF GPGAGGLHHA HSDAQGHLLF PGLPEQHGPH GSQNVLNGQM RLGLPGEVFG RSEQYRQVAS PRTDPYSAAQ LHNQYGPMNM N
ZIC2 (zinc finger protein of the cerebellum 2) is a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. In mouse, knockout of Zic1 leads to aplasia of cerebellum and skeletal abnormalities. Mutation in Zic2 and Zic3 in mouse and/or human cause holoprosencephaly and heterotaxis, respectively. Holoprosencephaly is the most common structural anomaly of the human brain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Zic family member 2 (odd-paired homolog, Drosophila); Zinc finger protein of the cerebellum 2; Zinc finger protein ZIC 2
基因别名: HPE5; ZIC2
UniProt ID: (Human) O95409
Entrez Gene ID: (Human) 7546