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Invitrogen
ZIC3 Polyclonal Antibody
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产品信息
PA5-29073
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human ZIC3. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.84 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: HepG2.
Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (93%), Xenopus laevis (92%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: heterotaxy 1; ZIC; Zic family member 3 (odd-paired homolog, Drosophila); ZIC1; ZIC2; Zinc finger protein 203; Zinc finger protein of the cerebellum 3; Zinc finger protein ZIC 3; ZNF201
基因别名: HTX; HTX1; RGD1561261; VACTERLX; ZIC3; ZNF203
UniProt ID: (Human) O60481
Entrez Gene ID: (Human) 7547, (Rat) 367944
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
metal ion binding
molecular_function
nucleic acid binding
C2H2 zinc finger transcription factor
heart looping
transcription from RNA polymerase II promoter
determination of left/right symmetry
anterior/posterior pattern specification
cell differentiation
lung development
somatic stem cell population maintenance
determination of pancreatic left/right asymmetry
determination of left/right asymmetry in nervous system
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
determination of digestive tract left/right asymmetry
determination of liver left/right asymmetry
pattern specification process
biological_process
