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Invitrogen
ZMIZ2 Polyclonal Antibody
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产品信息
PA5-31271
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human ZMIZ2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.93 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: IMR32.
Predicted reactivity: Mouse (92%), Rat (93%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PIAS-like protein Zimp7; Zinc finger MIZ domain-containing protein 2; zinc finger, MIZ-type containing 2
基因别名: HRIHFB2007; hZIMP7; KIAA1886; NET27; TRAFIP20; ZIMP7; ZMIZ2
UniProt ID: (Human) Q8NF64
Entrez Gene ID: (Human) 83637
