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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM1 is widely expressed in different tissues in eukaryotes under several forms derived by alternative splicing. While its function remains unknown, the related protein ZMYM2 has been shown to associate with and stabilize the LSD1-CoREST-HDAC1 (LCH) complex of chromatin through its MYM-type zinc fingers, thereby enhancing the transcriptional repression of several genes, suggesting that ZMYM1 may play a similar role.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: RP11-181E22.4; RP11-248I9.4; unnamed protein product; zinc finger, MYM domain containing 1; zinc finger, MYM-type 1
基因别名: 5830412B09Rik; MYM
UniProt ID: (Human) Q5SVZ6
Entrez Gene ID: (Human) 79830, (Rat) 313604, (Mouse) 68310