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Recommended positive controls: 293T, Jurkat.
Predicted reactivity: Zebrafish (93%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The ZNF503 gene encodes zinc finger protein 503, a transcription factor involved in the regulation of developmental processes and cellular differentiation. ZNF503 contains zinc finger domains that enable it to bind DNA and modulate the transcription of specific target genes, influencing pathways critical for embryonic development, particularly in the neural and mesenchymal tissues. It plays a substantial role in the regulation of stem cell differentiation and has been implicated in various biological processes, including neuronal migration, immune response, and organogenesis. Alterations in ZNF503 expression have been linked to developmental anomalies and diseases such as cancers, where it affects tumor growth and progression by modulating gene networks involved in cell proliferation and differentiation. Research into ZNF503 focuses on understanding its complex regulatory functions and potential as a target for therapeutic interventions in developmental disorders and oncological applications.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Zinc finger protein 503
基因别名: Nlz2; NOLZ-1; NOLZ1; ZNF503
UniProt ID: (Human) Q96F45
Entrez Gene ID: (Human) 84858