Search
Proteintech
ZNF521 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
产品信息
23716-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ZNF521 fusion protein Ag20540
偶联物
形式
Liquid
浓度
280 µg/mL
规格
42 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Sequence of this protein is as follows: THTSNKPYKC AICRRGFLSS SSLHGHMQVH ERNKDGSQSG SRMEDWKMKD TQKCSQCEEG FDFPEDLQKH IAECHPECSP NEDRAALQCV YCHELFVEET SLMNHMEQVH SGEKKNSCSI CSESFHTVEE LYSHMDSHQQ PESCNHSNSP SLVTVGYTSV SSTTPDSNLS VDSSTMVEAA PPIPKSRGRK RAAQQTPDMT GPSSKQAKVT YSCIYCNKQL FSSLAVLQIH LKTMHLDKPE QAHICQYCLE VLPSLY
靶标信息
The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Early hematopoietic zinc finger protein; LYST-interacting protein 3; unnamed protein product; Zinc finger protein 521
基因别名: EHZF; Evi3; LIP3; ZNF521
UniProt ID: (Human) Q96K83
Entrez Gene ID: (Human) 25925
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
