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Invitrogen
ZNF609 Polyclonal Antibody
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产品信息
PA5-59314
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SKEVGIPAPN AVATLPDNIK FVTPVPGPQG KEGKSKSKRS KSGKDTSKPT PGTSLFTPSE GAASKKEVQG RSGDGANAGG LVAAIAPKGS
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
靶标信息
The ZNF609 gene encodes zinc finger protein 609, which functions as a transcriptional regulator involved in the modulation of gene expression during development and cellular differentiation. ZNF609 contains zinc finger domains, which enable it to bind DNA and control the transcription of target genes, influencing processes such as cell proliferation and neuronal development. This gene is particularly important for normal neural and muscle cell function and has been implicated in neurodevelopmental disorders and cancer. ZNF609 is known to interact with signaling pathways that control neuron differentiation and migration, and alterations in its expression have been associated with conditions like intellectual disability and developmental delay. Furthermore, ZNF609's role in cancer biology shows its involvement in regulating genes linked to tumor progression and metastasis. Studies on ZNF609 focus on understanding its regulatory mechanisms and potential as a therapeutic target for diseases related to developmental deficits and cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Zinc finger protein 609
基因别名: KIAA0295; RGD1561651; ZNF609
UniProt ID: (Human) O15014
Entrez Gene ID: (Human) 23060, (Rat) 363412
