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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: CTPVVPTRIP AIVSLSRGPV SPLVRFQLPN VLFAYAHTLA LYHGGDDALL SDFCATLLGV SGALGAQQVF ASAEEAL
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%.
The ZNHIT2 gene, located on chromosome 7, encodes a zinc-finger HIT-type containing protein crucial for various cellular processes, such as chromatin remodeling and gene transcription regulation. Knockout studies in mice reveal that ZNHIT2, alongside ZNHIT1, is essential during early development, with deficits leading to embryonic lethality during peri-implantation stages due to reduced proportions of pluripotent inner cell mass cells and aberrant expression of key developmental genes like NANOG and SOX17. This gene's relevance extends to its involvement in protein-protein and protein-nucleic acid interactions that are fundamental in cellular functions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Protein FON; Zinc finger HIT domain-containing protein 2
基因别名: C11orf5; ZNHIT2
Entrez Gene ID: (Human) 741