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Invitrogen
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PA1-27905 detects CTNNA1 from human, mouse, rat, and chimpanzee samples.
PA1-27905 may be successfully used in Western blot applications. By Western blot, this antibody has only been tested on fusion protein.
The PA1-27598 immunogen is a synthetic peptide corresponding to human Alpha-1 catenin.
Alpha catenin is a member of the b-catenin family of cytosolic proteins. Alpha catenin interacts with N-cadherin and b-catenin on the cytosolic side of adherins junctions to mediate the interaction with the actin cytoskeleton. Alpha catenin is a homodimer in solution, but dissociates to form a 1:1 heterodimer with b-catenin in order to interact with cadherins. It also regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Alpha catenin also functions in the control of the startle modulation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。