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alpha MSH Polyclonal Antibody

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alpha MSH Polyclonal Antibody

产品信息

BS-1848R

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500-1:2,000
-

免疫组化（石蜡） (IHC (P))

1:200
-

酶联免疫吸附实验 (ELISA)

1:500-1:1,000
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide of human Alpha-MSH, amino acids 138-150.
3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

规格

100 µg

纯化类型

Protein A

保存液

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

内含物

0.02% ProClin 300

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

ACTH stimulates the adrenal glands to release cortisol. MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes. Beta-endorphin and Met-enkephalin are endogenous opiates.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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Cite this product

生物信息学

蛋白别名: adrenal corticotropic hormone; adrenocorticotropic hormone; adrenocorticotropic hormone precursor; adrenocorticotropin; alpha-melanocyte stimulating hormone; alpha-melanocyte-stimulating hormone; alpha-MSH; beta-endorphin; beta-LPH; beta-melanocyte-stimulating hormone; beta-MSH; corticotropin-like intermediary peptide; corticotropin-lipotropin; gamma-LPH; gamma-MSH; lipotropin beta; lipotropin gamma; melanotropin alpha; melanotropin beta; melanotropin gamma; met-enkephalin; opiomelanocortin prepropeptide; POMC; pro-ACTH-endorphin; pro-opiomelanocortin; pro-opiomelanocortin-alpha; prohormone; proopiomelanocortin (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin); proopiomelanocortin precursor; proopiomelanocortin preproprotein; proopiomelanocortin, beta (endorphin, beta); proopoimelanocortin, beta (endorphin, beta); unnamed protein product

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基因别名: ACTH; alpha-MSH; alphaMSH; BE; Beta-LPH; beta-MSH; CLIP; Gamma-LPH; gamma-MSH; LPH; MSH; NPP; OBAIRH; POC; Pomc-1; Pomc1; Pomc2

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UniProt ID: (Human) P01189, (Mouse) P01193

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Entrez Gene ID: (Human) 5443, (Mouse) 18976, (Rat) 24664

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功能
G-protein coupled receptor binding receptor binding hormone activity protein binding type 3 melanocortin receptor binding type 4 melanocortin receptor binding type 5 melanocortin receptor binding receptor agonist activity type 1 melanocortin receptor binding molecular_function
参与通路
generation of precursor metabolites and energy signal transduction adenylate cyclase-activating G-protein coupled receptor signaling pathway cell-cell signaling regulation of blood pressure calcium-mediated signaling positive regulation of glucocorticoid biosynthetic process regulation of appetite negative regulation of appetite negative regulation of tumor necrosis factor production cellular pigmentation positive regulation of exocytosis positive regulation of transcription from RNA polymerase II promoter positive regulation of melanin biosynthetic process negative regulation of immune response regulation of feeding behavior antimicrobial humoral immune response mediated by antimicrobial peptide positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of oxytocin production response to melanocyte-stimulating hormone negative regulation of inflammatory response to antigenic stimulus regulation of glycogen catabolic process positive regulation of cell proliferation killing of cells of other organism modification of morphology or physiology of other organism glucose homeostasis negative regulation of apoptotic process motor behavior positive regulation of neutrophil mediated killing of fungus negative regulation of eating behavior regulation of corticosterone secretion response to lipopolysaccharide cortisol secretion response to ethanol
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