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Nordic
beta-2 Glycoprotein 1 Polyclonal Antibody
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产品信息
RAHU-B2GP1
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Human beta-2 glycoprotein 1
偶联物
形式
Lyophilized
保存液
whole serum
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute the lyophilized antiserum by adding 1 mL sterile distilled water.
Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. Cross-reactivity of this antiSerum has not been tested in detail.
In immunoelectrophoresis use 2 µL human plasma or equivalent against 120 µL antiserum. In double radial immunodiffusion use a rosette arrangement with 10 µL antiserum in 3 mm diameter center well and 2 µL plasma samples (neat and serially diluted) in 2 mm diameter peripheral wells. In electroimmunodiffusion use 1 percent antiserum in the gel. Measured by quantitative precipitin analysis. The amount of beta2 glycoprotein 1 precipitated by 1 mL antiserum is approximately 0.2 mg.
Dilutions may be prepared by adding phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the antiserum. Diluted antiserum should be stored at 4°C, not refrozen, and preferably used the same day.
靶标信息
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2GPI; Activated protein C-binding protein; Anticardiolipin cofactor; APC inhibitor; Apo-H; Apolipoprotein H; apolipoprotein H (beta-2-glycoprotein I); B2GPI; beta(2)GPI; Beta-2-glycoprotein 1; Beta-2-glycoprotein I
基因别名: APOH; B2G1; B2GP1; BG
UniProt ID: (Human) P02749
Entrez Gene ID: (Human) 350
negative regulation of endothelial cell proliferation
platelet degranulation
triglyceride metabolic process
aging
blood coagulation, intrinsic pathway
negative regulation of endothelial cell migration
positive regulation of triglyceride catabolic process
negative regulation of angiogenesis
positive regulation of blood coagulation
negative regulation of blood coagulation
organ regeneration
plasminogen activation
negative regulation of myeloid cell apoptotic process
response to triglyceride
triglyceride transport
negative regulation of smooth muscle cell apoptotic process
positive regulation of lipoprotein lipase activity
regulation of fibrinolysis
negative regulation of fibrinolysis
negative regulation of respiratory burst
