Bioss

caspase-9 p10 Polyclonal Antibody

Name: caspase-9 p10 Polyclonal Antibody
Brand: Bioss
SKU: BS-8502R

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)

caspase-9 p10 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 2

caspase-9 p10 Antibody (BS-8502R) in IHC (P)

Formalin-fixed and paraffin embedded rat brain labeled with Anti Caspase-9 p10 Polyclonal Antibody, Unconjugated (bs-8502R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

caspase-9 p10 Antibody in Western Blot (WB)

Product Image Gallery

Immunogen image

Immunogen Image caspase-9 p10 Polyclonal Antibody

产品信息

BS-8502R

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200

免疫组化（石蜡） (IHC (P))

1:200

免疫组化（冰冻） (IHC (F))

1:100-1:500

免疫细胞化学 (ICC/IF)

1:50-1:200

流式细胞分析 (Flow)

1:20-1:100

酶联免疫吸附实验 (ELISA)

1:500-1:1,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide derived from human caspase-9 subunit p10, amino acids 351-416.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

内含物

0.02% ProClin 300

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: 25 kDa caspase-9 dominant negative protein; APAF-3; apoptotic protease activating factor 3; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; CASP-9; caspase 9, apoptosis-related cysteine peptidase; Caspase-9; caspase-9 dominant negative form; caspase-9-carboxyl-terminal divergent; ICE-LAP6; ICE-like apoptotic protease 6; protein phosphatase 1, regulatory subunit 56

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基因别名: AI115399; APAF-3; APAF3; AW493809; CASP-9; Casp-9-CTD; CASP9; Casp9_v1; Caspase-9; ICE-LAP6; MCH6; PPP1R56

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UniProt ID: (Human) P55211, (Mouse) Q8C3Q9

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Entrez Gene ID: (Human) 842, (Mouse) 12371, (Rat) 58918

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功能