Progen

delta Catenin Monoclonal Antibody (J19)

Name: delta Catenin Monoclonal Antibody (J19)
Brand: Progen
SKU: 651152

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说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

delta Catenin Antibody in Immunohistochemistry (IHC)

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delta Catenin Antibody (651152) in IHC

Immunohistochemistry of delta Catenin staining on human cerebral cortex (courtesy of The Human Protein Atlas, www.proteinatlas.org, Thul PJ et al, 2017. A subcellular map of the human proteome. Science).

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产品信息

651152

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

免疫组化 (IHC)

Assay-dependent

免疫组化（石蜡） (IHC (P))

Ready-to-use

免疫组化（冰冻） (IHC (F))

Ready-to-use

产品规格

种属反应

Bovine, Human, Mouse, Rat, Zebrafish

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

J19

抗原

Synthetic Peptide J6 (Corresponding To Aa 292-309), Coupled To Klh

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

Conc. Not Determined

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Recognizes neurojungin (delta-catenin,a unique 160 kD polypeptide of the plakoglobin/armadillo protein family) present in adhering type junctions in the nervous system, primarily expressed in the brain. Delta-catenin also binds to presenilin-1, mutations of this protein are described to play a role in familial Alzheimer's disease. No cross-reaction with other members of the armadillo/plakoglobin protein family. Polypeptide reacting: Neurojungin (delta-catenin), 160 kD polypeptide; in endothelia from blood vessels the antibody is positive with a 300 kD polypeptide.Reactivity on cultured cell lines: Murine cell line A1B2, A431 stably transfected with neurojungin cDNA. Positive control: Murine brain, retina.

靶标信息

Delta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Cadherin-associated Src substrate; Cadherin-associated Src substrate (CAS); CAS; Catenin (cadherin associated protein) delta 1; catenin (cadherin-associated protein), delta 1; Catenin delta-1; catenin src; catenin, delta 1; p120 catenin; P120 CTN; P120 p120; P120 P120CTN; p120(cas); p120(ctn); p120-catenin

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基因别名: AA409437; AU019353; CAS; Catns; CTNND; CTNND1; KIAA0384; mKIAA0384; P120; p120(CAS); p120(CTN); P120CAS; P120CTN

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UniProt ID: (Human) O60716, (Mouse) P30999