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Invitrogen
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Positive test controls include: U-87MG, A-549, HL-60, HT-1080, LO2, Mouse brain.
Immunogen sequence: TLPEGSVISL HPPDAEEDED DGEFSDDSGA DQEKDKVKMK GYNPAEVGAA GKGYLWKAAG MNMEEEEELQ QNLWGLKINM EEESESESEQ SMDSEEPDSR GGSPQMDDIK VFQNEVLGTL QRGKEENISC DNLVLEINSL KYAYNISLKE VMQVLSHVVL EFPLQQMDSP LDSSRYCALL LPLLKAWSPV FRNYIKRAAD HLEALAAIED FFLEHEALGI SMAKVLMAFY QLEILAEETI LSWFSQRDTT DKGQQLRKNQ QLQRFIQWLK EAEEESSEDD
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B, a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: eIF-2B GDP-GTP exchange factor subunit epsilon; eIF2B GDP-GTP exchange factor subunit epsilon; eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa; translation initiation factor eIF-2B subunit epsilon; Translation initiation factor eIF2B subunit epsilon
基因别名: C81315; CACH; CLE; EIF-2B; EIF2B5; EIF2BE; EIF2Bepsilon; LVWM
UniProt ID: (Human) Q13144, (Mouse) Q8CHW4
Entrez Gene ID: (Human) 8893, (Mouse) 224045