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Invitrogen
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PA1-27812 detects EIF3S2 from human and mouse samples.
PA1-27812 may be successfully used in ELISA and Western blot applications. By Western blot, this antibody has only been tested on fusion protein.
The PA1-27566 immunogen is a synthetic peptide corresponding to human Eukaryotic translation initiation factor 3 subunit 2.
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。