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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:1,000-1:2,000 | - |
免疫组化（石蜡） (IHC (P)) |
1:150 | - |
流式细胞分析 (Flow) |
1:100 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Mouse / IgG1 |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
OTI1F2 |
抗原 |
Full length human recombinant protein of EIF4E2 produced in HEK293T cell |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.66 mg/mL |
纯化类型 |
Affinity Chromatography |
保存液 |
PBS, pH 7.3, with 1% BSA, 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2724246 |
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation (PubMed:9582349, PubMed:17368478, PubMed:25624349). Acts as a repressor of translation initiation (PubMed:22751931). In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: eIF-4E type 2; eIF4E-like cap-binding protein; eIF4E-like protein 4E-LP; eukar; Eukaryotic translation initiation factor 4E homologous protein; Eukaryotic translation initiation factor 4E type 2; Eukaryotic translation initiation factor 4E-like 3; h4EHP; mRNA cap-binding protein 4EHP; mRNA cap-binding protein type 3
基因别名: 4E-LP; 4EHP; EIF4E2; EIF4EL3; IF4e
UniProt ID: (Human) O60573
Entrez Gene ID: (Human) 9470
分子生物学功能:
translation factor
translation initiation factor
translational protein
