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Proteintech
eRF3a/GSPT1 Monoclonal Antibody (2A3H6), CoraLite® Plus 488
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产品信息
CL488-68217
产品规格
种属反应
Human,
Mouse,
Pig,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
2A3H6
抗原
Recombinant protein
偶联物
激发/发射光谱
493/522 nm
形式
Liquid
纯化类型
Protein A
保存液
PBS with 50% glycerol, 0.5% BSA
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: FNRSVDGPIR LPIVDKYKDM GTVVLGKLES GSICKGQQLV MMPNKHNVEV LGILSDDVET DTVAPGENLK IRLKGIEEEE ILPGFILCDP NNLCHSGRTF DAQIVIIEHK SIICPGYNAV LHIHTCIEEV EITALICLVD KKSGEKSKTR PRFVKQDQVC IARLRTAGTI CLETFKDFPQ MGRFTLRDEG KTIAIGKVLK LVPEKD
靶标信息
eRF3a (eukaryotic peptide chain release factor subunit 3a), also known as GSPT1 (G1 to S phase transition 1), is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94% sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: eRF3a; Eukaryotic peptide chain release factor GTP-binding subunit ERF3A; Eukaryotic peptide chain release factor subunit 3a; eukaryotic polypeptide chain release factor 3; G1 to phase transition 1; G1 to S phase transition protein 1; G1 to S phase transition protein 1 homolog; G1-to-S phase transition 1; G1-to-S transition GTP binding protein; guanine nucleotide regulatory protein
基因别名: 551G9.2; AI314175; AI326449; AV307676; C79774; ERF3A; ETF3A; G1st; GSPT1; Gst-1; GST1
UniProt ID: (Human) P15170, (Mouse) Q8R050
Entrez Gene ID: (Pig) 100517817, (Human) 2935, (Rat) 24420, (Mouse) 14852
