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Invitrogen
gamma Actin Polyclonal Antibody, DyLight™ 488
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产品信息
PA5-22953
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
The epitope recognized by this antibody maps to the N-terminus of human Gamma-actin using the numbering given in Swiss-Prot entry P63261. The N-terminus of Gamma-Actin is highly conserved with Beta-Actin and preliminary indications are that NB
偶联物
激发/发射光谱
492/519 nm
查看光谱
形式
Liquid
浓度
0.2 mg/mL
保存条件
4°C, store in dark
运输条件
Wet ice
靶标信息
Actins are highly conserved proteins that are involved in various types of cell motility and in maintenance of the cytoskeleton. Three main groups of actin isoforms have been identified in vertebrate animals: alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. Actin gamma 1, encoded by this gene, is a cytoplasmic actin found in all cell types. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss and also with Baraitser-Winter syndrome. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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