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Invitrogen
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Immunogen sequence: FLLDGLSSQPL FNDIAAGIPS ITAYSKNGLK IEFTFERSNT NPSVTVITIQ ASNSTELDMT DFVFQAAVPK TFQLQLLSPS SSIVPAFNTG TI
Highest antigen sequence identity to the following orthologs - mouse 98%, rat 33%.
Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。