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Agrisera
hScrib/Protein LAP4 Polyclonal Antibody
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产品信息
AS06-155
产品规格
种属反应
Human
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
GST tagged C-terminus of hScrib including PDZ3 and 4 domains.
偶联物
形式
Lyophilized
保存液
whole serum
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
For reconstitution add 100 µL of sterile water.
Specific Species Reactivity: Human
靶标信息
SCRIB is a cytoplasmic multimodular scaffold protein targeted to epithelial adherens junctions and neuronal presynaptic compartments. SCRIB and its orthologs in vertebrates and invertebrates participate in cell polarization.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adaptor protein; CRIB1; hScrib; hSCRIB1-N1; KIAA0147; oSCRIB; Protein LAP4; Protein scribble homolog; S Vartul; SCRB1; SCRIB1; Scribble; scribbled homolog; scribbled planar cell polarity protein; Vartul
基因别名: CRIB1; KIAA0147; LAP4; oSCRIB; SCRB1; SCRIB; SCRIB1; VARTUL
UniProt ID: (Human) Q14160
Entrez Gene ID: (Human) 23513
establishment of T cell polarity
neural tube closure
positive regulation of receptor recycling
auditory receptor cell morphogenesis
regulation of translation
protein localization
cell proliferation
epithelial structure maintenance
positive regulation of epithelial to mesenchymal transition
synaptic vesicle targeting
morphogenesis of embryonic epithelium
cell migration
cochlear nucleus development
establishment of cell polarity
cell differentiation
polarized epithelial cell differentiation
positive regulation of interferon-gamma production
establishment or maintenance of apical/basal cell polarity
establishment of apical/basal cell polarity
post-anal tail morphogenesis
wound healing
positive regulation of apoptotic process
receptor clustering
astrocyte cell migration
establishment or maintenance of epithelial cell apical/basal polarity
negative regulation of mitotic cell cycle
negative regulation of translational initiation
negative regulation of activated T cell proliferation
synaptic vesicle endocytosis
positive chemotaxis
auditory receptor cell stereocilium organization
inner ear receptor stereocilium organization
apoptotic process involved in morphogenesis
mammary gland duct morphogenesis
protein localization to adherens junction
activation of GTPase activity
cell-cell adhesion
neurotransmitter receptor transport, endosome to postsynaptic membrane
vesicle-mediated transport in synapse
regulation of postsynaptic neurotransmitter receptor internalization
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