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Proteintech
hnRNP-E1 Polyclonal Antibody
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产品信息
14523-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
hnRNP-E1 Fusion Protein Ag6007 (1-356 aa encoded by BC039742)
偶联物
形式
Liquid
浓度
0.23 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MDAGVTESG LNVTLTIRLL MHGKEVGSII GKKGESVKRI REESGARINI SEGNCPERII TLTGPTNAIF KAFAMIIDKL EEDINSSMTN STAASRPPVT LRLVVPATQC GSLIGKGGCK IKEIRESTGA QVQVAGDMLP NSTERAITIA GVPQSVTECV KQICLVMLET LSQSPQGRVM TIPYQPMPAS SPVICAGGQD RCSDAAGYPH ATHDLEGPPL DAYSIQGQHT ISPLDLAKLN QVARQQSHFA MMHGGTGFAG IDSSSPEVKG YWASLDASTQ TTHELTIPNN LIGCIIGRQG ANINEIRQMS GAQIKIANPV EGSSGRQVTI TGSAASISLA QYLINARLSS EKGMGCS (1-356 aa encoded by BC039742)
靶标信息
This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular polydomains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Alpha-CP1; epididymis secretory protein Li 85; Heterogeneous nuclear ribonucleoprotein E1; heterogenous nuclear ribonucleoprotein E1; heterogenous nuclear ribonucleoprotein X; hnRNP E1; hnRNP-E1; Nucleic acid-binding protein SUB2.3; Poly(rC)-binding protein 1
基因别名: [a]CP-1; alphaCP-1; HEL-S-85; hnRNP-E1; hnRNP-X; HNRPE1; HNRPX; PCBP1; WBP17
UniProt ID: (Human) Q15365, (Mouse) P60335
Entrez Gene ID: (Human) 5093, (Mouse) 23983
