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Product Details
MA5-18024
Applications
Tested Dilution
Publications
产品规格
Species Reactivity
Human,
Mouse,
Xenopus
Host/Isotype
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1G11
Immunogen
proprietary immunogen
Conjugate
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.1% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
RRID
AB_2539408
Product Specific Information
For IHC applications, it is necessary to perform heat-mediated antigen retrieval with citrate buffer, pH 6, prior to staining. In Western blot applications, this antibody detects a band at ~53 kDa (hnRNP F, predicted 49.8 kDa) and 56 kDa (hnRNP H, predicted 53.9 kDa).
Target Information
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins. The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: Heterogeneous nuclear ribonucleoprotein F; Heterogeneous nuclear ribonucleoprotein F, N-terminally processed; hnRNP F; HnRNP F protein; HNRNPH1; mcs94 1; Nucleolin-like protein mcs94-1; ROF
Gene Aliases: 4833420I20Rik; AA407306; HNRNPF; HNRPF; mcs94-1; OK/SW-cl.23
UniProt ID: (Human) P52597, (Mouse) Q9Z2X1
Entrez Gene ID: (Human) 3185, (Mouse) 98758
Molecular Function:
RNA splicing factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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