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Proteintech
iASPP Polyclonal Antibody
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产品信息
18590-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
iASPP Fusion Protein Ag13273 (481-829 aa encoded by BC064913)
偶联物
形式
Liquid
浓度
0.32 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody could both recognize unphosphorylated and phosphorylated iASPP.
Immunogen sequence: EGPVARPLS PTRLQPALPP EAQSVPELEE VARVLAEIPR PLKRRGSMEQ APAVALPPTH KKQYQQIISR LFHRHGGPGP GGPEPELSPI TEGSEARAGP PAPAPPAPIP PPAPSQSSPP EQPQSMEMRS VLRKAGSPRK ARRARLNPLV LLLDAALTGE LEVVQQAVKE MNDPSQPNEE GITALHNAIC GANYSIVDFL ITAGANVNSP DSHGWTPLHC AASCNDTVIC MALVQHGAAI FATTLSDGAT AFEKCDPYRE GYADCATYLA DVEQSMGLMN SGAVYALWDY SAEFGDELSF REGESVTVLR RDGPEETDWW WAALHGQEGY VPRNYFGLFP RVKPQRSKV (481-829 aa encoded by BC064913)
靶标信息
IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53), whereas ASPP1. and ASPP2. are activators of p53.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: inhibitor of apoptosis stimulating protein of p53; Inhibitor of ASPP protein; NFkB interacting protein 1; NFkB-interacting protein 1; PPP1R13B-like protein; ppp1r13l; Protein iASPP; protein phosphatase 1, regulatory (inhibitor) subunit 13 like; protein phosphatase 1, regulatory subunit 13 like; RelA-associated inhibitor; retinoic acid induced 4
基因别名: AV260376; IASPP; NKIP1; PPP1R13BL; PPP1R13L; RAI; RAI4; wa3
UniProt ID: (Human) Q8WUF5, (Mouse) Q5I1X5
Entrez Gene ID: (Human) 10848, (Mouse) 333654, (Rat) 686781
negative regulation of transcription from RNA polymerase II promoter
cardiac right ventricle morphogenesis
ventricular cardiac muscle tissue development
transcription, DNA-templated
apoptotic process
post-embryonic development
embryonic camera-type eye development
multicellular organism growth
hair cycle
positive regulation of cell differentiation
multicellular organismal homeostasis
cardiac muscle contraction
cell-cell adhesion
regulation of signal transduction by p53 class mediator
regulation of transcription, DNA-templated
