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Nordic
inter alpha trypsin inhibitor Polyclonal Antibody
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产品信息
SHAHU-IATI
产品规格
种属反应
Human
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Human inter alpha trypsin inhibitor
偶联物
形式
Lyophilized
浓度
13 mg/mL
纯化类型
IgG Fraction
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store at 4° C or -20°C. The working antibody solution is stable for at least 7 days at 4°C. Precautions should be taken for storage for longer periods. Problems of long term stability may occur with highly diluted solutions. No other preservative agent has been added to the present formulation. For long storage purposes in solution the addition of sodium azide to 0.02 % is advised with the appropriate precautions of use.
Precipitation assays: In immunoelectrophoresis in agarose-plates use 2 µL human plasma or equivalent against 120 µL antiserum. In double radial immunodiffusion use a rosette arrangement with 10 µL antiserum in 3 mm diameter center well and 2 µL plasma samples (neat and serially diluted) in 2 mm diameter peripheral wells. In electroimmunodiffusion (Laurell) use a concentration of 1% of the antiserum in the gel.
Species Reactivity: The antiserum does not cross-react with any other Human plasma proteins as tested in gel-diffusion techniques. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail.
Reconstitute the lyophilized antiserum by adding 1 mL sterile distilled water.
靶标信息
Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screen for and diagnose Cystic Fibrosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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