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This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
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Recommended positive controls: MDCK, HepG2, mouse liver, rat brain.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
AFDN belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Afadin; Afadin adherens junction formation factor; ALL1-fused gene from chromosome 6 protein; myeloid/lymphoid or mixed lineage-leukemia translocation to 4 homolog; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4; myeloid/lymphoid or mixed-lineage leukemia 4; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4; Protein AF-6
基因别名: 5033403D15Rik; Af-6; AF6; Afadin; AFDN; Gm314; I-afadin; MLL-AF6; MLLT4; S-afadin
UniProt ID: (Human) P55196, (Mouse) Q9QZQ1, (Rat) O35889
Entrez Gene ID: (Dog) 431695, (Human) 4301, (Mouse) 17356, (Rat) 26955
分子生物学功能: non-motor actin binding protein