Invitrogen

mGLuR4 Recombinant Rabbit Monoclonal Antibody (6H26L4)

mGLuR4 Antibody in Immunocytochemistry (ICC/IF)

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mGLuR4 Antibody (702603) in ICC/IF

For immunofluorescence analysis, HEK-293 cells were stably transfected with human mGLuR4. After 24hr of transfection the cells were fixed and permeabilized for detection of endogenous mGLuR4 using Anti-mGLuR4 Recombinant Rabbit Monoclonal Antibody (Product # 702603, 1 µg/mL, 1:500 dilution) and labeled with Goat anti-Rabbit IgG (H+L) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate. Panel a) shows representative cells that were stained for detection of membrane localization of the mGLuR4 on the transfected cells. The images were... View More

mGLuR4 Antibody in Immunohistochemistry (IHC)

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产品信息

702603

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500

免疫组化 (IHC)

1:500

免疫细胞化学 (ICC/IF)

1:500

产品规格

种属反应

Human, Rat

宿主/亚型

Rabbit / IgG

Expression System

Expi293

分类

Recombinant Monoclonal

类型

Antibody

克隆号

6H26L4

抗原

Peptide corresponding to human mGLUR4 [aa891-aa912]

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2734819

产品详细信息

This antibody is predicted to react with Monkey, Pig, Rabbit, Cat.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

靶标信息

The Metabotropic Glutamate Receptor mGluR4/GRM4 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties.

仅用于科研。不用于诊断过程。未经明确授权不得转售。