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Invitrogen
p57 Kip2 Polyclonal Antibody
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产品信息
PA5-32532
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide derived from N-terminus of human p57/kip2 protein.
偶联物
形式
Liquid
浓度
0.021 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.6, with 1% BSA
内含物
0.1% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Heat-mediated antigen retrieval is recommended prior to staining, using a 1mM EDTA buffer, pH 8.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is placenta or hydatid mole.
靶标信息
This gene is part of a gene cluster on chromosome Xp11.23. The encoded protein contains a zinc finger motif often found in transcriptional regulators, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Beckwith Wiedemann syndrome (WBS); Cyclin dependent kinase inhibitor 1C (CDKN1C); Cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (p57, Kip2); Cyclin-dependent kinase inhibitor p57; IMAGE; p57 Kip2; p57Kip2
基因别名: BWCR; BWS; CDKN1C; KIP2; p57; p57Kip2; WBS
UniProt ID: (Human) P49918
Entrez Gene ID: (Human) 1028
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
kidney development
cell cycle arrest
regulation of mitotic cell cycle
aging
myeloid cell differentiation
adrenal gland development
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of kinase activity
multicellular organism growth
negative regulation of phosphorylation
neuron maturation
camera-type eye development
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
negative regulation of epithelial cell proliferation
digestive system development
uterus development
embryonic placenta morphogenesis
genetic imprinting
negative regulation of protein serine/threonine kinase activity
