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Proteintech
p57Kip2 Monoclonal Antibody (1A12H3)
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产品信息
66794-1-IG
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat,
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1A12H3
抗原
p57Kip2 Fusion Protein Ag19927 (1-316 aa encoded by BC067842)
偶联物
形式
Liquid
浓度
0.7 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSDASLRST STMERLVARG TFPVLVRTSA CRSLFGPVDH EELSRELQAR LAELNAEDQN RWDYDFQQDM PLRGPGRLQW TEVDSDSVPA FYRETVQVGR CRLLLAPRPV AVAVAVSPPL EPAAESLDGL EEAPEQLPSV PVPAPASTPP PVPVLAPAPA PAPAPVAAPV AAPVAVAVLA PAPAPAPAPA PAPAPVAAPA PAPAPAPAPA PAPAPAPDAA PQESAEQGAN QGQRGQEPLA DQLHSGISGR PAAGTAAASA NGAAIKKLSG PLISDFFAKR KRSAPEKSSG DVPAPCPSPS AAPGVGSVEQ TPRKRLR (1-316 aa encoded by BC067842)
靶标信息
This gene is part of a gene cluster on chromosome Xp11.23. The encoded protein contains a zinc finger motif often found in transcriptional regulators, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Beckwith Wiedemann syndrome (WBS); Cyclin dependent kinase inhibitor 1C (CDKN1C); Cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (p57, Kip2); Cyclin-dependent kinase inhibitor p57; IMAGE; p57 Kip2; p57Kip2; p57KIP2 A3sh
基因别名: AL024410; BWCR; BWS; CDKI; CDKN1C; KIP2; p57; p57(kip2); p57KIP2; WBS
UniProt ID: (Human) P49918, (Mouse) P49919
Entrez Gene ID: (Human) 1028, (Mouse) 12577, (Rat) 246060
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
kidney development
cell cycle arrest
regulation of mitotic cell cycle
aging
myeloid cell differentiation
adrenal gland development
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of kinase activity
multicellular organism growth
negative regulation of phosphorylation
neuron maturation
camera-type eye development
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
negative regulation of epithelial cell proliferation
digestive system development
uterus development
embryonic placenta morphogenesis
genetic imprinting
negative regulation of protein serine/threonine kinase activity
placenta development
cell cycle
phosphorylation
