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Invitrogen
pho Polyclonal Antibody
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pho Antibody (PA5-144384) in WB
Western blot analysis of pho in recombinant protein using a dilution of 1:2,000. Samples were incubated with pho polyclonal antibody (Product # PA5-144384). Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 45 kDa. Observed band size: 45 kDa.
产品信息
PA5-144384
产品规格
种属反应
Fruit fly
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Drosophila melanogaster (Fruit fly) pho protein (1-250aa )
偶联物
形式
Liquid
浓度
3.05 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% Proclin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Polycomb group (PcG) protein that binds to the 5'-CNGCCATNNNNG-3' sequence found in the regulatory regions of many genes. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. Probably targets the Esc/E(z) complex to DNA. Necessary but not sufficient to recruit a functional PcG repressive complex that represses target genes, suggesting that the recruitment of the distinct PRC1 complex is also required to allow a subsequent repression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CG17743-PA; CG17743-PB; peiohomeotic; PHO; pho-PA; pho-PB; pleihomeotic; pleohomeotic; Polycomb protein PHO; Polycomb protein PHO pho CG17743; polyhomeotic; Protein pleiohomeotic; RE17954p; Transcription factor YY1 homolog; zinc finger protein
基因别名: CG17743; Dmel\CG17743; Dmel_CG17743; dYY1; l(4)102EFc; l(4)29; l(4)BU-2; l(4)OC-1; l(4)pho; PHO; PHO/YY1; YY1
UniProt ID: (Fruit fly) Q8ST83
Entrez Gene ID: (Fruit fly) 43819
RNA polymerase II core promoter proximal region sequence-specific DNA binding
DNA binding
chromatin binding
protein binding
chromatin DNA binding
sequence-specific DNA binding
DNA-binding transcription factor
zinc finger transcription factor
C2H2 zinc finger transcription factor
gene-specific transcriptional regulator
