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Human ALDH1A1 quantitates human ALDH1A1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human ALDH1A1.
ALDH1A1 belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : ALDC, ALDH-E1, ALDH1, ALDH11, HEL-9, HEL-S-53e, HEL12, PUMB1, RALDH1
基因ID : (Human) 216
基因符号 : ALDH1A1
蛋白别名 : 3-deoxyglucosone dehydrogenase, acetaldehyde dehydrogenase 1, aldehyde dehydrogenase 1 (EC 1.2.1.3), Aldehyde dehydrogenase 1 soluble, epididymis secretory sperm binding protein Li53e, MGC2318, aldehyde dehydrogenase 1, soluble, aldehyde dehydrogenase, liver cytosolic, ALDH class 1, ALHDII, epididymis luminal protein 12, epididymis luminal protein 9, epididymis secretory sperm binding protein Li 53e, oxidoreductase, RALDH 1, retinal dehydrogenase 1, retinaldehyde dehydrogenase 1, unnamed protein product
UniProt ID (Human) P00352