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Human Alpha 2-M quantitates human Alpha 2-M in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Alpha 2-M.
Alpha 2-Macroglobulin (a2M), is a approximately 720-kDa homotetrameric glycoprotein composed of four identical approximately 180 kDa subunits. aAlpha 2M shares with other alpha-macroglobulins, like the complement components C3 and C4 and the pregnancy zone protein PZP, an extraordinary binding capacity for a variety of ligands. This allows the alpha-macroglobulins to serve as humoral defense barriers against foreign peptides in the plasma. Alpha 2M interacts and captures virtually any proteinase, often referred to as a panprotease inhibitor. In the brain of Alzheimer's disease (AD) patients, Alpha 2M also has been localized to diffuse amyloid plaques, supporting an important role for alpha 2M in AD etiopathology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : A2M, A2MD, CPAMD5, FWP007, S863-7
基因ID : (Human) 2
基因符号 : A2M
蛋白别名 : Alpha-2-M, Alpha-2-macroglobulin, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5
UniProt ID (Human) P01023