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Human Carboxylesterase 1/CES1 quantitates human Carboxylesterase 1/CES1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Carboxylesterase 1/CES1.
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : ACAT, CE-1, CEH, CES1, CES2, hCE-1, HMSE, HMSE1, PCE-1, REH, SES1, TGH
基因ID : (Human) 1066
基因符号 : CES1
蛋白别名 : ACAT, acyl coenzyme A:cholesterol acyltransferase, Acyl-coenzyme A:cholesterol acyltransferase, Brain carboxylesterase hBr1, Carboxylesterase 1, carboxylesterase 1 (monocyte/macrophage serine esterase 1), carboxylesterase 2 (liver), CE-1, CEH, Cholesteryl ester hydrolase, Cocaine carboxylesterase, Egasyn, HMSE, human monocyte/macrophage serine esterase 1, Liver carboxylesterase 1, Methylumbelliferyl-acetate deacetylase 1, Monocyte/macrophage serine esterase, REH, Retinyl ester hydrolase, Serine esterase 1, TGH, Triacylglycerol hydrolase
UniProt ID (Human) P23141