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Invitrogen
Human Complement C5b-9 (soluble) ELISA Kit
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产品规格
检测灵敏度
18.75 ng/mL
测定范围
31.25-2,000
检测样本类型/体积
{Plasma=100 µL, Serum=100 µL}
手工操作时间
1 hr 20 min
总时间
2 hr 30 min
均相（无需洗涤）
No
批间差异
<10%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated microwell plate
Standard
Biotinylated Detection Antibody
Streptavidin-HRP
Standard and Sample Diluent
Biotinylated Detection Antibody Diluent
HRP Conjugate Diluent
Wash Buffer Concentrate
Stop Solution
Substrate Solutio
Adhesive Plate Covers
Standard
Biotinylated Detection Antibody
Streptavidin-HRP
Standard and Sample Diluent
Biotinylated Detection Antibody Diluent
HRP Conjugate Diluent
Wash Buffer Concentrate
Stop Solution
Substrate Solutio
Adhesive Plate Covers
运输条件
Wet ice
储存
At 2-8°C for one year. Protect from light. Do not freeze.
蛋白名称
Complement C5b-9
均相（无需洗涤）
Human
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
The Human sC5b-9 (Soluble Terminal Complement Complex C5b-9) ELISA quantitates sC5b-9 in serum, plasma, and other biological fluids.
靶标信息
The complement system is a fundamental part of innate immunity, consisting of over 45 genes that encode various complement components, regulators, and receptors. The complement C5b-9 complex, also known as the Membrane Attack Complex (MAC), plays a crucial role in the immune defense mechanism. It includes the sequential assembly of proteins C5b, C6, C7, C8, and multiple copies of C9. This complex forms transmembrane channels that puncture the cell membrane of target cells, leading to cell lysis. Specifically, MAC has significant implications in mediating cell death in both pathogenic organisms and cancer cells. The genes involved are clustered across the human genome, mainly organized in three significant loci. The understanding of the C5b-9 complex's function extends beyond its antimicrobial roles to include its interactions with tumor cells, where it can induce cell death and influence cancer progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : ARMD15, C5, C5a, C5b, C5D, C6, C7, C9, C9D, CPAMD4, ECLZB
基因ID : (Human) 727, (Human) 729, (Human) 730, (Human) 735
基因符号 : C5, C6, C7, C9
蛋白别名 : anaphylatoxin C5a analog, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, C5a anaphylatoxin, C5b-9, MAC Complex, Membrane Attack Complex, Complement C5, Complement component C6, Complement component C7, Complement component C9, prepro-C5
UniProt ID (Human) P01031, (Human) P13671, (Human) P10643, (Human) P02748
