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Human CytokeRatin 8/KRT8 quantitates human Cytokeratin 8/KRT8 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Cytokeratin 8/KRT8.
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CARD2, CK-8, CK8, CYK8, K2C8, K8, KO, KRT8
基因ID : (Human) 3856
基因符号 : KRT8
蛋白别名 : CK-8, Cytokeratin-8, K8, keratin 8, type II, Keratin, type II cytoskeletal 8, Keratin-8, Type-II keratin Kb8
UniProt ID (Human) P05787