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Invitrogen
Human EN-RAGE/S100A12 ELISA Kit
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产品规格
检测灵敏度
0.82 ng/mL
测定范围
0.82-600 ng/mL
检测样本类型/体积
{Supernatant=50 µL, Plasma=50 µL, Serum=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
蛋白名称
S100A12
均相（无需洗涤）
Human
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Human EN-RAGE/S100A12 quantitates human EN-RAGE/S100A12 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human EN-RAGE/S100A12.
靶标信息
S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A12 is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. S100A12 is also a ligand for RAGE. Interaction with RAGE on mononuclear phagocytes, lymphocytes and endothelium triggers cellular activation. Nuclear factor kappa B, a key transcription factor for inflammatory events, is activated by S100A12/RAGE. S100A12 has also been shown to have anti-microbial properties.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : CAAF1, CAGC, CGRP, ENRAGE, MRP-6, MRP6, p6, S100A12
基因ID : (Human) 6283
基因符号 : S100A12
蛋白别名 : CAAF1, CAGC, calcitermin, Calcium-binding protein in amniotic fluid 1, calgranulin C, Calgranulin-C, CGRP, EN RAGE, Protein S100 A12, EN-RAGE, Extracellular newly identified RAGE-binding protein, Migration inhibitory factor-related protein 6, MRP-6, Neutrophil S100 protein, Protein S100-A12, S100 calcium-binding protein A12, S100 calcium-binding protein A12 (calgranulin C)
UniProt ID (Human) P80511
