Search Thermo Fisher Scientific
Human Glypican 3 quantitates human Glypican 3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Glypican 3.
GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : DGSX, GPC3, GTR2-2, MXR7, OCI-5, OCI5, SDYS, SGB, SGBS, SGBS1
基因ID : (Human) 2719
基因符号 : GPC3
蛋白别名 : glypican proteoglycan 3, Glypican-3, GTR2-2, heparan sulphate proteoglycan, Intestinal protein OCI-5, MXR7, secreted glypican-3
UniProt ID (Human) P51654