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Human IGFBP-rp1/IGFBP-7 quantitates human IGFBP-rp1/IGFBP-7 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IGFBP-rp1/IGFBP-7.
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : AGM, FSTL2, IBP-7, IGFBP-7, IGFBP-7v, IGFBP7, IGFBPRP1, MAC25, PSF, RAMSVPS, TAF
基因ID : (Human) 3490
基因符号 : IGFBP7
蛋白别名 : angiomodulin, IBP-7, IBP7, IGFBP, IGFBP rP1, Insulin like growth factor binding protein, IGF-binding protein 7, IGFBP-rP1, insulin-like growth factor binding protein 7, Insulin-like growth factor-binding protein 7, MAC25 protein, PGI2-stimulating factor, Prostacyclin-stimulating factor, TAF, Tumor-derived adhesion factor
UniProt ID (Human) Q16270