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The Human Interleukin 1 Receptor 2 (Hu IL-1R2/IL-1RB) ELISA quantitates Hu IL-1R2 in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu IL-1R2.
原理方法
The Human IL-1R2 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
严格验证
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2, IL1R2c, IL1RB
基因ID : (Human) 7850
基因符号 : IL1R2
蛋白别名 : antigen CDw121b, CD121 antigen-like family member B, CD121b, CDw121b, IL-1 type II receptor, IL-1R-2, IL-1R-beta, ILR2, interleukin 1 receptor type II variant 3, interleukin 1 receptor, type II, Interleukin-1 receptor beta, Interleukin-1 receptor type 2, Interleukin-1 receptor type II, type II interleukin-1 receptor, beta
UniProt ID (Human) P27930