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Human KIRREL3 quantitates human KIRREL3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human KIRREL3.
The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. The protein encoded by this gene is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : KIAA1867, KIRRE, KIRREL3, MRD4, NEPH2, PRO4502, UNQ5923/PRO4502/PRO19814
基因ID : (Human) 84623
基因符号 : KIRREL3
蛋白别名 : Kin of IRRE-like protein 3, Kin of irregular chiasm-like protein 3, nephrin-like 2, Nephrin-like protein 2
UniProt ID (Human) Q8IZU9