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Human L1CAM quantitates human L1CAM in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human L1CAM.
L1CAM/CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CAML1, CD171, HSAS, HSAS1, L1CAM, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, S10, SPG1
基因ID : (Human) 3897
基因符号 : L1CAM
蛋白别名 : antigen identified by monoclonal antibody R1, CD 171, CD171 molecule, sCD171, sL1 CAM, sL1CAM, soluble CD 171, soluble CD171, soluble L1 CAM, soluble L1CAM, CD171, N-CAM-L1, Neural cell adhesion molecule L1
UniProt ID (Human) P32004