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Human NTB-A/SLAMF6 quantitates human NTB-A/SLAMF6 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human NTB-A/SLAMF6.
Ly108, the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6), is expressed on NK cells, B cells, and T cells. Engagement of the Ly108 receptor enhances NK cell activity and increases the expression of IFN-gamma. This receptor plays a role in the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. In Ly108 knock-out mice, CD4+ T cells show a diminished ability to produce IL-4 and exhibit defective neutrophil functions, indicating the importance of Ly108 in immune regulation and cellular function. Overall, Ly108 is crucial for modulating immune responses and maintaining effective immune cell activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000
基因ID : (Human) 114836
基因符号 : SLAMF6
蛋白别名 : activating NK receptor, natural killer-, T- and B-cell antigen, NK-T-B-antigen, NTBA receptor, unnamed protein product
UniProt ID (Human) Q96DU3