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产品规格
检测灵敏度
0.42 ng/mL
测定范围
0.42-100 ng/mL
检测样本类型/体积
{Supernatant=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Colorimetric Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
2-8°C
蛋白名称
Nogo-A
均相（无需洗涤）
Human
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Human Nogo-A/Reticulon 4A quantitates human Nogo-A/Reticulon 4A in supernatant. The assay will exclusively recognize both natural and recombinant human Nogo-A/Reticulon 4A.
靶标信息
NogoA is a member of a family of integral membrane proteins termed reticulons that are thought to be involved in numerous disorders including neurodegenerative diseases. Reticulon proteins are known to regulate many cellular processes and interact with multiple proteins and receptors such as BACE. NogoA was initially identified as a myelin-associated neurite outgrowth inhibitor. It is highly expressed in oligodendrocytes in the white matter of the CNS, blocking its activity with antibodies or other factors results in improved axon regrowth and functional recovery in experimental CNS lesion models. NogoA has also been suggested to play a role in neurodegenerative diseases such as Amyotrophic lateral sclerosis, in which case NogoA is found at elevated levels in postmortem muscular samples, and multiple sclerosis (MS), in which case autoantibodies to NogoA have been found in serum and cerebrospinal fluid in MS patients.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : ASY, KIAA0886, My043, Nbla00271, Nbla10545, NI220/250, NOGO, NOGO-A, Nogo-B, Nogo-C, NOGOC, NSP, NSP-CL, RTN-X, RTN4, RTN4-A, RTN4-B1, RTN4-B2, RTN4-C, SP1507
基因ID : (Human) 57142
基因符号 : RTN4
蛋白别名 : Foocen, Human NogoA, My043 protein, neurite growth inhibitor 220, Neurite outgrowth inhibitor, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, Nogo protein, NSP, reticulon 5, Reticulon-4, Reticulon-5, RTN-x
UniProt ID (Human) Q9NQC3
