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Human Olfactomedin-2/Noelin-2 quantitates human Olfactomedin-2/Noelin-2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Olfactomedin-2/Noelin-2.
Involved in transforming growth factor beta (TGF-beta)-induced smooth muscle differentiation. TGF-beta induces expression and nuclear translocation of OLFM2 where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes. Plays a role in AMPAR complex organization.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : NOE2, NOELIN2, NOELIN2_V1, OlfC, OLFM2
基因ID : (Human) 93145
基因符号 : OLFM2
蛋白别名 : neuronal olfactomedin related ER localized protein 2, Noelin-2, Olfactomedin-2
UniProt ID (Human) O95897