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Invitrogen
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Human PEAR1 quantitates human PEAR1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human PEAR1.
Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated; the tyrosine phosphorylation can be inhibited by eptifibatide, an aIIbbeta3 antagonist that also inhibits platelet aggregation. Recent studies have indicated that genetic variations in PEAR1, may be associated with enhanced agonist-induced platelet aggregation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : JEDI, MEGF12
基因ID : (Human) 375033
基因符号 : PEAR1
蛋白别名 : multiple EGF-like domains protein 12, multiple EGF-like-domains 12, multiple epidermal growth factor-like domains protein 12, RP11-107D16.3, unnamed protein product
UniProt ID (Human) Q5VY43