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Human PLA2G2A quantitates human PLA2G2A in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human PLA2G2A.
The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : MOM1, PLA2, PLA2B, PLA2G2A, PLA2L, PLA2S, PLAS1, RASF-A, sPLA2
基因ID : (Human) 5320
基因符号 : PLA2G2A
蛋白别名 : GIIC sPLA2, Group IIA phospholipase A2, Non-pancreatic secretory phospholipase A2, NPS-PLA2, Phosphatidylcholine 2-acylhydrolase 2A, phospholipase A2, group IIA (platelets, synovial fluid), Phospholipase A2, membrane associated
UniProt ID (Human) P14555