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Human Park7/DJ-1 quantitates human Park7/DJ-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Park7/DJ-1.
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : DJ-1, DJ1, GATD2, HEL-S-67p
基因ID : (Human) 11315
基因符号 : PARK7
蛋白别名 : epididymis secretory sperm binding protein Li 67p, FLJ27376, FLJ34360, FLJ92274, OTTHUMP00000001350, OTTHUMP00000001351, PARK7 GENE, PARK7/DJ1, CTA-215D11.1, early onset 7, maillard deglycase, oncogene DJ1, Parkinson disease (autosomal recessive, early onset) 7, parkinson protein 7, protein deglycase DJ-1, protein DJ-1, protein/nucleic acid deglycase DJ-1, unnamed protein product
UniProt ID (Human) Q99497