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Human Properdin quantitates human Properdin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Properdin.
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : BFD, CFP, PFC, PFD, PROPERDIN
基因ID : (Human) 5199
基因符号 : CFP
蛋白别名 : Complement factor P, Properdin, properdin P factor, complement
UniProt ID (Human) P27918