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Human SHBG quantitates human SHBG in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human SHBG.
SHBG is a steroid binding protein that was first described as a plasma protein secreted by the liver and is thought to participate in the regulation of steroid responses. SHBG transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Low plasma SHBG levels are associated with obesity, abdominal adiposity, metabolic syndrome, and predict the development of type 2 diabetes. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : ABP, SBP, SHBG, TEBG
基因ID : (Human) 6462
基因符号 : SHBG
蛋白别名 : ABP, SBP, Sex hormone-binding globulin, Sex hormone-binding globulin (SHBG), Sex steroid binding protein (SBP), Testosterone binding beta globulin, Testosterone-Estradiol-Binding Globulin (TEBG), Androgen binding protein (ABP), Sex steroid-binding protein, SHBG, TeBG, Testis-specific androgen-binding protein, testosterone-binding beta-globulin, Testosterone-estradiol-binding globulin, Testosterone-estrogen-binding globulin
UniProt ID (Human) P04278