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The Human TFPI Rapid ELISA Kit quantitates TFPI in serum and plasma
Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : EPI, LACI, TFI, TFPI, TFPI1
基因ID : (Human) 7035
基因符号 : TFPI
蛋白别名 : anti-convertin, EPI, Extrinsic pathway inhibitor, LACI, Lipoprotein-associated coagulation inhibitor, lipoprotein-associated coagulation inhibitor precursor, OTTHUMP00000205431, OTTHUMP00000163472, TFPI, Tissue factor pathway inhibitor, tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor), unnamed protein product
UniProt ID (Human) P10646