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Human TrkA quantitates human TrkA in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human TrkA.
NTRK1 (TRKA) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : MTC, NTRK1, p140-TrkA, TRK, Trk-A, TRK1, TRKA
基因ID : (Human) 4914
基因符号 : NTRK1
蛋白别名 : gp140trk, High affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor type 1, neurotrophic tyrosine kinase, receptor, type 1, Oncogene TRK, p140-TrkA, Trk-A, TRK1-transforming tyrosine kinase protein, Tropomyosin-related kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A
UniProt ID (Human) P04629